Fosamax: 7 things you should know
Sep 11, · Fosamax is a brand-name prescription medication. It’s FDA-approved for the following uses in adults: prevent or treat osteoporosis (a condition that causes brittle, weak bones) in women who’ve gone. Oct 19, · Fosamax (Alendronate) Last Updated: October 19, Alendronate is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure. This medicine is for use when you have a high /5.
Medically reviewed by Carmen Fookes, BPharm. Last updated on What is the drug fosamax used for 9, If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side ksed you are more likely to experience include:.
Note: In general, seniors or children, people with certain medical conditions such as liver or kidney problems, heart disease, diabetes, seizures or people who take other medications are more at risk of developing a wider range of side effects. View complete list of side effects. Fosamax helps to reduce the risk of fracture in people with osteoporosis and some other bone conditions. Dosage instructions, including remaining upright for at least 30 minutes and taking with a full glass of water, must be strictly followed.
The optimal length of therapy remains unknown. Medicines that interact with Fosamax may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with Fosamax.
An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed. Note that this list is not all-inclusive and includes only common medications that may interact with Fosamax. How to improve french vocabulary should refer to the prescribing information for Fosamax for a complete list of interactions.
Fosamax alendronate [Package Insert]. Remember, uesd this and all other medicines out of the reach of children, never share your medicines with others, and use Fosamax only for the indication prescribed. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Patient Tips Fksamax Print Save. How it works Fosamax is a brand trade name for alendronate. Alendronate strengthens frug and may be used for the treatment or prevention of osteoporosis.
Alendronate works by inhibiting osteoclasts fosamaax are responsible for breaking down and reabsorbing bone by a process known as bone resorption. Alendronate strengthens bones by slowing down bone loss and allowing osteoblasts bone-building cells to work more effectively, improving bone mass.
Fosamax belongs to a group of medicines tne as bisphosphonates. Upsides Fosamax is used in the treatment and prevention of osteoporosis in postmenopausal women and men. Fosamax may also be used to treat glucocorticoid-induced osteoporosis and Paget's disease of the bone.
Fosamax may also be used to treat adverse skeletal effects caused by some cancers. Some studies have shown that Fosamax may be more effective than other bisphosphonates such as risedronate at increasing bone mineral density and reducing bone turnover without a higher risk of side effects. Depending on the condition being treated and the dosage used, Fosamax may be taken once daily or once weekly.
Fosamax is available as a generic under the name alendronate. Alendronate tablets are available in a wider range of strengths Fosamax is only available as a 70mg tablet. Downsides If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Abdominal pain, bone muscle or joint pain, dyspepsia, hair loss, itch, how to grow your small business rapidly online, diarrhea, flatulence, dizziness, headache, vertigo, and swelling of the ankles or feet are the most common side effects.
Fosamax, like other bisphosphonates, may cause irritation of the esophagus and stomach. Some cases have been severe enough to warrant hospitalization. The risk is greater in people who lie down soon after taking Fosamax or who don't take it with a full glass of water. Take exactly as directed. Fosamax should be taken with a full glass of water and the person taking Fosamax should remain upright for at least 30 minutes after taking it. Severe bone, joint, or muscle pain, necessitating discontinuation of Fosamax in some people, has been reported, occurring from one day to several months after starting the drug.
Rarely may cause other side effects including uveitis eye inflammation. May not be suitable for some people including those with kidney disease, pre-existing esophageal conditions, low blood ror levels hypocalcemia rosamax, or who are unable to stand or sit upright for at least 30 minutes.
There are concerns about the long-term safety of bisphosphonates such as Fosamax as long-term use has been associated with atypical femur fractures, osteonecrosis of the jaw, and esophageal cancer. Fracture risk reduction may also persist for years after treatment has stopped. The optimal duration of therapy with Fosamax has not been established.
Periodically re-evaluate the need for therapy. Discontinuation of therapy should be considered by doctors after 3 to 5 years in patients at low risk of fracture. Fosamax may interact with antacids foszmax supplements containing calcium or magnesium. Fosamax may lower calcium levels in the blood.
Pre-existing low blood calcium levels should be corrected before Fosamax administration. Fosamax is only available as a 70mg tablet. This may limit the range of indications Fosamax can be used for. What does ana direct positive mean liquid preparation of Fosamax has been discontinued. View complete list of side effects 4. Bottom Line Fosamax helps to reduce the risk of fracture in people with osteoporosis and some other bone conditions.
Tips Take Fosamax at least 30 minutes before eating or drinking any food or beverages other than wateror taking any other medication, including calcium, antacids, or vitamins. Take Fosamax with a full glass of water and remain upright for at how to unlock a sidekick 2 for free 30 minutes.
Do not lie down. Do not substitute water with mineral water, coffee, soda, juice, or use. Never take Fosa,ax at bedtime. Take Fosamax exactly as directed by your doctor. Do not fosajax or decrease the dosage without your doctor's advice. Avoid eating, drinking other than wateror taking other medications for 30 minutes after taking Fosamax.
You may need to take supplementary calcium or vitamin D if your dietary intake is inadequate. Your doctor will advise you about this. If you are taking supplemental calcium, iron, magnesium, or antacids, take them at a different time of day to Fosamax for example at lunchtimeas they may interfere with the absorption of Fosamax. Note that mineral water may contain a higher concentration of calcium than tap or bottled water, and you should only drink if your doctor has confirmed it is compatible with Fosamax.
Talk to both your dentist and doctor if you require dental surgery or tooth extraction and you have been on Fosamax long-term. They may advise discontinuation of Fosamax.
Tell your doctor if you experience any thigh or groin pain, muscle cramps or twitches, severe or debilitating muscle pain, eye inflammation, or any other adverse effects of concern while you are taking Fosamax. Response and Effectiveness Fosamax starts to affect markers that reflect bone resorption within one month of dhat and reaches a plateau by three to six months.
Effects remain stable following continued treatment for up to three years. Food can significantly decrease the absorption of Fosamax. Interactions Medicines that interact with Fosamax may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with Fosamax. Common medications that may interact with Fosamax include: aluminum salts amikacin angiogenesis inhibitors, such as bevacizumab or everolimus aspirin calcium supplements chemotherapy agents for cancer diuretics, such as bumetanide and furosemide hormone replacement therapy iron salts lithium magnesium salts NSAIDs, such as ibuprofen, diclofenac, and naproxen olsalazine oral steroids, such as dexamethasone, prednisone, and methylprednisone sirolimus and tacrolimus zinc salts.
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Dec 03, · Alendronate (Fosamax) is in a drug class of medications called bisphosphonates. Fosamax is prescribed for treating osteoporosis, bone pain from diseases such as breast cancer, multiple myeloma, and Paget's disease. Dosing, side effects, warnings and precautions, and safety during pregnancy should be reviewed prior to taking this medication. Fosamax (alendronate sodium) is a prescription drug used to treat and prevent osteoporosis in adults. It was first introduced to the U.S. market in by the drug manufacturer Merck. Fosamax is a member of a class of medications called bisphosphonates which work to alter the cycle through which bone is formed and broken down within the body.
It is classified as a bisphosphonate which works to change the way bone is formed in the body and which may cause serious side effects such as esophageal cancer, osteonecrosis of the jaw, bone fractures and other serious conditions. Drug manufacturer, Merck has faced thousands of Fosamax lawsuits due to injuries caused by the medication. Those who suffer bone loss from osteoporosis or from steroid use are considered to be ideal candidates for Fosamax, however Fosamax may cause severe side effects, including esophageal cancer, osteonecrosis of the jaw, and unusual bone fractures.
Drug manufacturer Merck has faced thousands of Fosamax lawsuits filed by people or loved ones of those who were injured after taking the medication. It is also alleged that thousands of patients taking Fosamax did not actually face serious bone conditions but were encouraged to use the drug as a preventative treatment which may have contributed to unnecessary harm for many patients.
Fosamax alendronate sodium is a prescription drug used to treat and prevent osteoporosis in adults. It was first introduced to the U. Fosamax is a member of a class of medications called bisphosphonates which work to alter the cycle through which bone is formed and broken down within the body. This is thought to help prevent fractures and reverse bone loss. Fosamax can be taken in a liquid or pill form and may be given weekly or as smaller daily doses.
Because it may cause esophageal erosion and stomach problems, Fosamax has certain restrictions for use. It must be taken in the morning at least 30 minutes before eating or drinking anything other than water and patients must stand or sit upright for at least 30 minutes after taking Fosamax. The U. These warnings have also resulted in a number of changes to drug labeling and inclusion of new safety information or warnings about risks of the medication.
Thousands of Fosamax lawsuits have been filed for similar reasons. Side effects of Fosamax can range from moderate to severe. Patients taking Fosamax commonly experience stomach pains and irritation of the gastrointestinal lining, as well joint, muscle, and bone pains. In , the FDA released a Drug Safety Communication warning the public of the potential increased risk of sustaining fractures in the femur, or thigh bone, in bisphosphonate patients.
Though Fosamax is given to prevent bone loss and fractures, in some cases, Fosamax side effects may contribute to weakened and broken bones. These low-impact fractures have often occurred without extreme stress on the bone. The majority of Fosamax fractures occur in female patients and may occur during routine, non-stressful physical activities. Reports indicate that Fosamax femur fractures tend to occur spontaneously and may occur during low impact activity.
These areas are typically not associated with osteoporosis fractures but are unique to drug side effects. Furthermore, the femur is one of the strongest bones in the body, making Fosamax femur fractures more unusual. In March , the U. Food and Drug Administration FDA conducted an investigation on bisphosphonate drugs like Fosamax and their association with femur fractures.
The research indicated that rare but serious Fosamax femur fractures are associated with long-term use. The study was also published in the Journal of Bone and Mineral Research. The study examined patients who suffered femur breaks. The results showed that 94 percent of these were caused by Fosamax or other bisphosphonate drugs. Furthermore, the Fosamax femur fractures occurred in patients who had been taking Fosamax for an average of five or more years.
The study revealed that a main warning sign of a Fosamax femur fracture is persistent pain in the thigh or groin where the fracture will typically take place. The exact explanation for the incidence of Fosamax femur fractures is currently unknown.
However, it is believed that Fosamax alters the natural process of bone remodeling in the body. When small fractures occur, they accumulate and contribute to severe Fosamax femur fractures.
In theory, frozen bone can contribute to the clean fractures that many Fosamax patients experience. Another Fosamax user reported that her femur broke during a commute to work when the subway train she was traveling in came to a routine stop. Sue Heller of Colorado broke both femur bones during her 10 years of Fosamax treatment. Sandy Potter of New York reported that her femur broke completely in half while jumping rope with neighborhood children.
Also called dead jaw syndrome, Osteonecrosis is a Fosamax side effect which may cause the jawbone to degrade and collapse. Severe injury can occur as a result of small cuts or wounds in the mouth such as those caused by dental work. A small opening in the tissue over the jaw can become severely infected. This causes the gradual death of the bone. Some users have reported collapse after small breaks in the jawbone. The esophagus is the tube that carries food, liquid, and saliva to the stomach after they are swallowed.
Fosamax may cause inflammation and irritation of the esophagus which may result in serious damage, including development of bleeding esophageal ulcers. In severe cases, Fosamax side effects include esophageal erosion and perforation of the esophagus. Merck, the manufacturer of Fosamax, recommends that users take Fosamax with a large glass of water. Users should also stand or sit upright for at least 30 minutes after Fosamax treatment to avoid esophageal Fosamax side effects.
In some cases, damage to the esophagus may result in development of esophageal cancer. Conditions such as these show an increased risk of esophageal cancer. Other Fosamax side effects include low blood calcium levels and musculoskeletal pain. Low blood calcium is also referred to as hypocalcemia. This means that a Fosamax patient receives less calcium deposited back into the blood stream.
Many users also report Fosamax side effects such as musculoskeletal pain. Many patients experience this Fosamax side effect within days of beginning treatment. For many, the musculoskeletal pain subsides when treatment is discontinued. However, some patients continue to experience musculoskeletal pain even after Fosamax treatment. Fosamax is known to interact with certain medications.
Those who take aspirin or non-steroidal anti-inflammatory drugs NSAIDs such as ibuprofen and naproxen may experience stomach irritation. Iron and magnesium supplements have been known to prevent Fosamax absorption into the body. Additionally, antacids can make Fosamax less effective. Pharmaceutical giant, Merck, manufacturer of Fosamax has faced thousands of Fosamax lawsuits over the life of the drug.
Reports of injuries associated with Fosamax use began shortly after the drug was introduced, however once research proved the link between Fosamax and osteonecrosis of the jaw, lawsuits against Merck began to be filed. Injuries cited in Fosamax lawsuits have included fractures, esophagus issues, musculoskeletal pain, and osteonecrosis of the jaw. Another femur fracture federal lawsuits have not yet been settled.
In state courts, a group of over 3, femur fracture lawsuits was consolidated into Multicounty litigation MCL in New Jersey in and has yet to be settled. A number of the included cases were dismissed and reinstated and though several bellwether trials have resulted in awards for the plaintiffs, no large settlements have been announced. Nearly Fosamax femur-fracture lawsuits were also filed in state courts California and though the first case was settled for Merck, most have yet to be decided.
Home Fosamax. What Is Fosamax? Thousands of Fosamax lawsuits have been filed for similar reasons Fosamax Side Effects Side effects of Fosamax can range from moderate to severe. Fosamax Bone Fractures Though Fosamax is given to prevent bone loss and fractures, in some cases, Fosamax side effects may contribute to weakened and broken bones.
Fosamax Femur Fracture Reports indicate that Fosamax femur fractures tend to occur spontaneously and may occur during low impact activity. Theories for Fosamax Femur Fracture The exact explanation for the incidence of Fosamax femur fractures is currently unknown. Fosamax Osteonecrosis of the Jaw Also called dead jaw syndrome, Osteonecrosis is a Fosamax side effect which may cause the jawbone to degrade and collapse.
Fosamax Esophagus Side Effects The esophagus is the tube that carries food, liquid, and saliva to the stomach after they are swallowed. Esophageal Cancer In some cases, damage to the esophagus may result in development of esophageal cancer.
Other Fosamax Side Effects Other Fosamax side effects include low blood calcium levels and musculoskeletal pain. Fosamax side effects from hypocalcemia include: Nausea Fatigue Softened bones Foot and hand spasms Muscular cramps Abdominal cramps Muscular weakness Many users also report Fosamax side effects such as musculoskeletal pain.
Fosamax Drug Interactions Fosamax is known to interact with certain medications. Fosamax Lawsuits Pharmaceutical giant, Merck, manufacturer of Fosamax has faced thousands of Fosamax lawsuits over the life of the drug.